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301por Chinnakannan, Senthil K., Cargill, Tamsin N., Donnison, Timothy A., Ansari, M. Azim, Sebastian, Sarah, Lee, Lian Ni, Hutchings, Claire, Klenerman, Paul, Maini, Mala K., Evans, Tom, Barnes, Eleanor“…To develop a therapeutic HBV vaccine that can induce high magnitude T cells to all major HBV antigens, we have developed a novel HBV vaccine using chimpanzee adenovirus (ChAd) and modified vaccinia Ankara (MVA) viral vectors encoding multiple HBV antigens. …”
Publicado 2020
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302por Gella, Laxmi, Pal, Swakshyar Saumya, Ganesan, Suganeswari, Sharma, Tarun, Raman, Rajiv“…MATERIALS AND METHODS: A subset of 668 subjects from Sankara Nethralaya Diabetic Retinopathy (DR) Epidemiology and Molecular Genetics Study II, a population-based study, were included in the current study. …”
Publicado 2015
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303por Kaufman, Howard L, Taback, Bret, Sherman, William, Kim, Dae Won, Shingler, William H, Moroziewicz, Dorota, DeRaffele, Gail, Mitcham, Josephine, Carroll, Miles W, Harrop, Richard, Naylor, Stuart, Kim-Schulze, Seunghee“…A modified vaccinia virus Ankara (MVA) encoding 5T4 was tested in combination with high-dose IL-2 to determine the safety, objective response rate and effect on humoral and cell-mediated immunity. …”
Publicado 2009
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304por Currier, JR, De Souza, M, Ratto-Kim, S, Paris, R, Nguay, V, Cox, J, Earl, P, Moss, B, Sriplienchan, S, Thongcharoen, P, Kim, J, Robb, M, Michael, N, Marovich, MEnlace del recurso
Publicado 2009
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305por Castillo-Olivares, Javier, Calvo-Pinilla, Eva, Casanova, Isabel, Bachanek-Bankowska, Katarzyna, Chiam, Rachael, Maan, Sushila, Nieto, Jose Maria, Ortego, Javier, Mertens, Peter Paul Clement“…We initially characterised AHSV infection in this model, then tested the protective efficacy of a recombinant vaccine based on modified vaccinia Ankara expressing AHS-4 VP2 (MVA-VP2).…”
Publicado 2011
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306por Rampling, Tommy, Ewer, Katie J., Bowyer, Georgina, Bliss, Carly M., Edwards, Nick J., Wright, Danny, Payne, Ruth O., Venkatraman, Navin, de Barra, Eoghan, Snudden, Claudia M., Poulton, Ian D., de Graaf, Hans, Sukhtankar, Priya, Roberts, Rachel, Ivinson, Karen, Weltzin, Rich, Rajkumar, Bebi-Yassin, Wille-Reece, Ulrike, Lee, Cynthia K., Ockenhouse, Christian F., Sinden, Robert E., Gerry, Stephen, Lawrie, Alison M., Vekemans, Johan, Morelle, Danielle, Lievens, Marc, Ballou, Ripley W., Cooke, Graham S., Faust, Saul N., Gilbert, Sarah, Hill, Adrian V. S.“…Thirty-seven healthy malaria-naive adults were vaccinated with either a chimpanzee adenovirus 63 and modified vaccinia virus Ankara–vectored vaccine expressing a multiepitope string fused to TRAP and 3 doses of RTS,S/AS01(B) (group 1; n = 20) or 3 doses of RTS,S/AS01(B) alone (group 2; n = 17). …”
Publicado 2016
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307por Hu, Xintao, Valentin, Antonio, Cai, Yanhui, Dayton, Frances, Rosati, Margherita, Ramírez-Salazar, Eric G., Kulkarni, Viraj, Broderick, Kate E., Sardesai, Niranjan Y., Wyatt, Linda S., Earl, Patricia L., Moss, Bernard, Mullins, James I., Pavlakis, George N., Felber, Barbara K.“…In another cohort of animals, the study shows that a single inoculation with non-replicating recombinant Modified Vaccinia Ankara (rMVA62B) also potently boosted CE-specific responses after around 1.5 years of rest. …”
Publicado 2018
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308por Butler, Chris, Ellis, Chris, Folegatti, Pedro M., Swayze, Hannah, Allen, Julie, Bussey, Louise, Bellamy, Duncan, Lawrie, Alison, Eagling-Vose, Elizabeth, Yu, Ly-Mee, Shanyinde, Milensu, Mair, Catherine, Flaxman, Amy, Ewer, Katie, Gilbert, Sarah, Evans, Thomas G.“…Methods: This was a multicentre, participant- and safety assessor-blinded, randomised, placebo-controlled trial of the co-administration of Modified Vaccinia Ankara encoding nucleoprotein and matrix protein 1 (MVA-NP+M1) and annual influenza vaccine in participants ≥ 65. …”
Publicado 2021
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309por Chiuppesi, Flavia, Zaia, John A, Frankel, Paul H, Stan, Rodica, Drake, Jennifer, Williams, Brenda, Acosta, Anne Marie, Francis, Karyn, Taplitz, Randy A, Dickter, Janet K, Dadwal, Sanjeet, Puing, Alfredo G, Nanayakkara, Deepa D, Ash, Patricia, Cui, Yujie, Contreras, Heidi, La Rosa, Corinna, Tiemann, Katrin, Park, Yoonsuh, Medina, Joybelle, Iniguez, Angelina, Zhou, Qiao, Karpinski, Veronica, Johnson, Daisy, Faircloth, Katelyn, Kaltcheva, Teadora, Nguyen, Jenny, Kha, Mindy, Nguyen, Vu H, Francisco, Sandra Ortega, Grifoni, Alba, Wong, Angela, Sette, Alessandro, Wussow, Felix, Diamond, Don J“…BACKGROUND: COH04S1, a synthetic attenuated modified vaccinia virus Ankara vector co-expressing SARS-CoV-2 spike and nucleocapsid antigens, was tested for safety and immunogenicity in healthy adults. …”
Publicado 2022
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310por Goldstein, Neil, Bockstal, Viki, Bart, Stephan, Luhn, Kerstin, Robinson, Cynthia, Gaddah, Auguste, Callendret, Benoit, Douoguih, Macaya“…BACKGROUND: This phase 1 placebo-controlled study assessed the safety and immunogenicity of 2-dose regimens of Ad26.ZEBOV (adenovirus serotype 26 [Ad26]) and MVA-BN-Filo (modified vaccinia Ankara [MVA]) vaccines with booster vaccination at day 360. …”
Publicado 2020
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317por Carson, Connor, Antoniou, Maria, Ruiz-Argüello, Maria Begoña, Alcami, Antonio, Christodoulou, Vasiliki, Messaritakis, Ippokratis, Blackwell, Jenefer M., Courtenay, Orin“…Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK) against Leishmania major challenge in mice, which was consistent with results from TRYP protein/adjuvant combinations in non-human primates. …”
Publicado 2009
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318por Eitz Ferrer, Pedro, Potthoff, Stephanie, Kirschnek, Susanne, Gasteiger, Georg, Kastenmüller, Wolfgang, Ludwig, Holger, Paschen, Stefan A., Villunger, Andreas, Sutter, Gerd, Drexler, Ingo, Häcker, Georg“…F1L, encoded by the orthopoxvirus modified vaccinia virus Ankara (MVA) has a Bcl-2-like structure. An MVA mutant lacking F1L (MVAΔF1L) induces apoptosis, indicating that MVA infection activates and F1L functions to inhibit the apoptotic pathway. …”
Publicado 2011
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319por Bauza, Karolis, Malinauskas, Tomas, Pfander, Claudia, Anar, Burcu, Jones, E. Yvonne, Billker, Oliver, Hill, Adrian V. S., Reyes-Sandoval, Arturo“…The clinically relevant vectors modified vaccinia virus Ankara (MVA) and the chimpanzee adenovirus ChAd63 are promising delivery systems for malaria vaccines due to their safety profiles and proven ability to induce protective immune responses against Plasmodium falciparum thrombospondin-related anonymous protein (TRAP) in clinical trials. …”
Publicado 2014
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320por Dai, Peihong, Wang, Weiyi, Cao, Hua, Avogadri, Francesca, Dai, Lianpan, Drexler, Ingo, Joyce, Johanna A., Li, Xiao-Dong, Chen, Zhijian, Merghoub, Taha, Shuman, Stewart, Deng, Liang“…Modified vaccinia virus Ankara (MVA) is an attenuated poxvirus that has been engineered as a vaccine against infectious agents and cancers. …”
Publicado 2014
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