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1861por López-Gil, Elena, Lorenzo, Gema, Hevia, Esther, Borrego, Belén, Eiden, Martin, Groschup, Martin, Gilbert, Sarah C., Brun, Alejandro“…METHODOLOGY/PRINCIPAL FINDINGS: In this work, we evaluated the immunogenicity and protective efficacy of recombinant plasmid DNA and modified vaccinia virus Ankara (rMVA) vectored vaccines against Rift Valley fever in mice. …”
Publicado 2013
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1862por Fournillier, Anne, Frelin, Lars, Jacquier, Emilie, Ahlén, Gustaf, Brass, Anette, Gerossier, Estelle, Holmström, Fredrik, Broderick, Kate E., Sardesai, Niranjan Y., Bonnefoy, Jean-Yves, Inchauspé, Geneviève, Sällberg, Matti“…We explored the concept of heterologous prime/boost vaccination using 2 therapeutic vaccines currently in clinical development aimed at treating chronically infected hepatitis C virus (HCV) patients: prime with a DNA-based vaccine expressing HCV genotype 1a NS3/4A proteins (ChronVac-C) and boost with a modified vaccinia virus Ankara vaccine expressing genotype 1b NS3/4/5B proteins (MVATG16643). …”
Publicado 2013
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1863por Sheibley, Richard W., Enache, Mihaela, Swarzenski, Peter W., Moran, Patrick W., Foreman, James R.“…Diatom assemblages in a single sediment core from Hoh Lake (Olympic National Park) displayed a shift to increased relative abundances of Asterionella formosa and Fragilaria tenera beginning in the 1969–1975 timeframe, whereas these species were not found at the remaining (nine) sites. …”
Publicado 2014
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1864por Azap, Alpay, Bozkurt, Gülden Yılmaz, Yüksel, Meltem Kurt, Kutlu, Hakan, Topçuoğlu, Pervin, Aypak, Adalet, Akan, Hamdi“…Material and Methods: All cancer patients that received antineoplastic chemotherapy at Ankara University, School ofMedicine, Department of Hematology between May 2004 and May 2005 and developed neutropenia were included in thestudy. …”
Publicado 2012
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1865por Harris, Stephanie A., Satti, Iman, Matsumiya, Magali, Stockdale, Lisa, Chomka, Agnieszka, Tanner, Rachel, O'Shea, Matthew K., Manjaly Thomas, Zita-Rose, Tameris, Michele, Mahomed, Hassan, Scriba, Thomas J., Hanekom, Willem A., Fletcher, Helen A., McShane, Helen“…BCG-vaccinated South African infants were randomized to receive modified vaccinia virus Ankara, expressing the Mycobacterium tuberculosis antigen 85A (MVA85A), or placebo. …”
Publicado 2014
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1866por Weger-Lucarelli, James, Chu, Haiyan, Aliota, Matthew T., Partidos, Charalambos D., Osorio, Jorge E.“…METHODOLOGY/PRINCIPAL FINDINGS: In this study, we describe the construction and characterization of a modified Vaccinia virus Ankara (MVA) virus expressing CHIKV E3 and E2 proteins (MVA-CHIK) that protected several mouse models from challenge with CHIKV. …”
Publicado 2014
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1867“…Demographic data, indications and results for cases that received TB-PT at the Ankara Tuberculosis Control Dispensary No. 7 between 2008 and 2011 were retrospectively evaluated. …”
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1868por de Barra, Eoghan, Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Hennigan, Kerrie, Collins, Ann, Berrie, Eleanor, Lawrie, Alison M., Gilbert, Sarah C., Nicosia, Alfredo, McConkey, Samuel J., Hill, Adrian V. S.“…METHODOLOGY: We conducted a Phase Ia, non-randomized, clinical trial in 24 healthy, malaria-naïve adults of the chimpanzee adenovirus 63 (ChAd63) and modified vaccinia virus Ankara (MVA) replication-deficient viral vectored vaccines encoding the circumsporozoite protein (CS) of P. falciparum. …”
Publicado 2014
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1869Improved oxidative status in major abdominal surgery patients after N-acetyl cystein supplementationpor Kuyumcu, Aygun, Akyol, Asli, Buyuktuncer, Zehra, Ozmen, M Mahir, Besler, Halit Tanju“…METHODS: Thirty-three patients diagnosed with pancreas, stomach, rectum, colon malignancies, and undergoing major abdominal surgery at Ankara Numune Training and Research Hospital were randomly divided into two groups; control (CON) and N-acetyl cysteine (NAC). …”
Publicado 2015
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1870por Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Edwards, Nick J., Rampling, Thomas, Anagnostou, Nicholas A., de Barra, Eoghan, Havelock, Tom, Bowyer, Georgina, Poulton, Ian D., de Cassan, Simone, Longley, Rhea, Illingworth, Joseph J., Douglas, Alexander D., Mange, Pooja B., Collins, Katharine A., Roberts, Rachel, Gerry, Stephen, Berrie, Eleanor, Moyle, Sarah, Colloca, Stefano, Cortese, Riccardo, Sinden, Robert E., Gilbert, Sarah C., Bejon, Philip, Lawrie, Alison M., Nicosia, Alfredo, Faust, Saul N., Hill, Adrian V. S.“…Heterologous prime-boost with the viral vectors simian adenovirus 63 (ChAd63)-modified vaccinia virus Ankara (MVA) is the most potent inducer of T-cells in humans, demonstrating significant efficacy when expressing the preerythrocytic antigen insert multiple epitope–thrombospondin-related adhesion protein (ME-TRAP). …”
Publicado 2015
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1871por Doganer, Yusuf Cetin, Aydogan, Umit, Ongel, Kurtulus, Sari, Oktay, Koc, Bayram, Saglam, Kenan“…MATERIALS AND METHODS: The study was performed in three elementary schools in Ankara, Turkey between January and May 2011. It was planned to have 2500 students of 6–14 ages in the study. …”
Publicado 2015
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1872“…SETTINGS: The cohort study described here was carried out in and around Ankara the capital of Turkey, because of the considerable heterogeneity of the population in terms of traditional Middle Eastern and ‘modern’ Western lifestyle and social environment. …”
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1873por Ternette, Nicola, Block, Peter D., Sánchez-Bernabéu, Álvaro, Borthwick, Nicola, Pappalardo, Elisa, Abdul-Jawad, Sultan, Ondondo, Beatrice, Charles, Philip D., Dorrell, Lucy, Kessler, Benedikt M., Hanke, Tomáš“…Here, we evaluated the immunopeptidome of Jurkat cells infected with the vaccine candidate MVA.HIVconsv, which delivers HIV-1 conserved antigenic regions by using modified vaccinia virus Ankara (MVA). We employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify 6,358 unique peptides associated with the class I human leukocyte antigen (HLA), of which 98 peptides were derived from the MVA vector and 7 were derived from the HIVconsv immunogen. …”
Publicado 2015
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1874“…Our results indicate that the Kuroshio Current would have contributed to the sculpting of the phylogeographic structure by shaping genetic gaps between isolated populations. In addition, the Tokara Strait would have created a geographic barrier between the Ryukyu Islands and mainland Japan. …”
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1875“…These include a prime-boost regimen with RTS,S/AS02A and modified vaccinia virus Ankara (MVA) expressing the CSP antigen, and a DNA-prime, MVA-boost regimen expressing the ME TRAP antigens. …”
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1876por Badamchi-Zadeh, Alexander, McKay, Paul F., Holland, Martin J., Paes, Wayne, Brzozowski, Andrzej, Lacey, Charles, Follmann, Frank, Tregoning, John S., Shattock, Robin J.“…METHODS: We used a range of heterologous prime-boost vaccinations with DNA, Adenovirus, modified vaccinia Ankara (MVA) and protein vaccines based on the major outer membrane protein (MOMP) as an antigen, and investigated the effect of vaccine route, antigen and regimen on the induction of anti-chlamydial antibodies detectable in the ocular lavage fluid of mice. …”
Publicado 2015
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1877“…METHODS: A cross-sectional study was conducted with second (286; 83.1%) and third (275; 80.2%) year students at the Ankara University School of Medicine. The SRL perception (SRLP) scale and self-efficacy for problem-based learning (SPBL) scale were used in the study. …”
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1878por Payne, Ruth O., Silk, Sarah E., Elias, Sean C., Milne, Kathryn H., Rawlinson, Thomas A., Llewellyn, David, Shakri, A. Rushdi, Jin, Jing, Labbé, Geneviève M., Edwards, Nick J., Poulton, Ian D., Roberts, Rachel, Farid, Ryan, Jørgensen, Thomas, Alanine, Daniel G.W., de Cassan, Simone C., Higgins, Matthew K., Otto, Thomas D., McCarthy, James S., de Jongh, Willem A., Nicosia, Alfredo, Moyle, Sarah, Hill, Adrian V.S., Berrie, Eleanor, Chitnis, Chetan E., Lawrie, Alison M., Draper, Simon J.“…Safety and immunogenicity of replication-deficient chimpanzee adenovirus serotype 63 (ChAd63) and modified vaccinia virus Ankara (MVA) viral vectored vaccines targeting PvDBP_RII (Salvador I strain) were assessed in an open-label dose-escalation phase Ia study in 24 healthy UK adults. …”
Publicado 2017
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1879por Bunyasi, E. W., Luabeya, A. K. K., Tameris, M., Geldenhuys, H., Mulenga, H., Landry, B. S., Scriba, T. J., Schmidt, B-M., Hanekom, W. A., Mahomed, H., McShane, H., Hatherill, M.“…OBJECTIVE: To evaluate the long-term effectiveness of infant modified vaccinia Ankara virus-expressing antigen 85A (MVA85A) vaccination against tuberculosis (TB). …”
Publicado 2017
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1880por Stading, Ben R., Osorio, Jorge E., Velasco-Villa, Andres, Smotherman, Michael, Kingstad-Bakke, Brock, Rocke, Tonie E.“…With the goal of managing disease in free-ranging bats, we tested modified vaccinia Ankara (MVA) and raccoon poxvirus (RCN) as potential vaccine vectors in the Brazilian Free-tailed bat (Tadarida brasiliensis), using biophotonic in vivo imaging and immunogenicity studies. …”
Publicado 2016
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