Reducing Agent‐Mediated Nonenzymatic Conversion of 2‐Oxoglutarate to Succinate: Implications for Oxygenase Assays

por Khan, Amjad, Schofield, Christopher J., Claridge, Timothy D. W.
Publicado 2020

Torsional and Electronic Factors Control the C−H⋅⋅⋅O Interaction

por Driver, Russell W., Claridge, Timothy D. W., Scheiner, Steve, Smith, Martin D.
Publicado 2016

Protein-ligand binding affinity determination by the waterLOGSY method: An optimised approach considering ligand rebinding

por Huang, Renjie, Bonnichon, Arnaud, Claridge, Timothy D. W., Leung, Ivanhoe K. H.
Publicado 2017

Global Aromaticity and Antiaromaticity in Porphyrin Nanoring Anions

por Peeks, Martin D., Jirasek, Michael, Claridge, Timothy D. W., Anderson, Harry L.
Publicado 2019

Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles

por Smart, Tristan J., Hamed, Refaat B., Claridge, Timothy D.W., Schofield, Christopher J.
Publicado 2020

Anomalous Nuclear Overhauser Effects in Carbon-Substituted Aziridines: Scalar Cross-Relaxation of the First Kind**

por Kuprov, Ilya, Hodgson, David M, Kloesges, Johannes, Pearson, Christopher I, Odell, Barbara, Claridge, Timothy D W
Publicado 2015

Impact of Multiple Hydrogen Bonds with Fluoride on Catalysis: Insight from NMR Spectroscopy

por Ibba, Francesco, Pupo, Gabriele, Thompson, Amber L., Brown, John M., Claridge, Timothy D. W., Gouverneur, Véronique
Publicado 2020

Single-Acetylene Linked Porphyrin Nanorings

por Rickhaus, Michel, Vargas Jentzsch, Andreas, Tejerina, Lara, Grübner, Isabell, Jirasek, Michael, Claridge, Timothy D. W., Anderson, Harry L.
Publicado 2017

Biocatalytic production of bicyclic β-lactams with three contiguous chiral centres using engineered crotonases

por Hamed, Refaat B., Gomez-Castellanos, J. Ruben, Henry, Luc, Warhaut, Sven, Claridge, Timothy D. W., Schofield, Christopher J.
Publicado 2019

(19)F NMR Monitoring of Reversible Protein Post‐Translational Modifications: Class D β‐Lactamase Carbamylation and Inhibition

por van Groesen, Emma, Lohans, Christopher T., Brem, Jürgen, Aertker, Kristina M. J., Claridge, Timothy D. W., Schofield, Christopher J.
Publicado 2019

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by (19)F NMR Spectroscopy**

por Rydzik, Anna M, Brem, Jürgen, van Berkel, Sander S, Pfeffer, Inga, Makena, Anne, Claridge, Timothy D W, Schofield, Christopher J
Publicado 2014

Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative C...

por Probert, Fay, Walsh, Alissa, Jagielowicz, Marta, Yeo, Tianrong, Claridge, Timothy D W, Simmons, Alison, Travis, Simon, Anthony, Daniel C
Publicado 2018

Monitoring protein-metal binding by (19)F NMR – a case study with the New Delhi metallo-β-lactamase 1

por Rydzik, Anna M., Brem, Jürgen, Chandler, Shane A., Benesch, Justin L. P., Claridge, Timothy D. W., Schofield, Christopher J.
Publicado 2020

Oxygenase-Catalyzed Desymmetrization of N,N-Dialkyl-piperidine-4-carboxylic Acids**

por Rydzik, Anna M, Leung, Ivanhoe K H, Kochan, Grazyna T, McDonough, Michael A, Claridge, Timothy D W, Schofield, Christopher J
Publicado 2014

Cephalosporins inhibit human metallo β-lactamase fold DNA repair nucleases SNM1A and SNM1B/apollo

por Lee, Sook Y., Brem, Jürgen, Pettinati, Ilaria, Claridge, Timothy D. W., Gileadi, Opher, Schofield, Christopher J., McHugh, Peter J.
Publicado 2016

Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice

por Larkin, James R., Dickens, Alex M., Claridge, Timothy D. W., Bristow, Claire, Andreou, Kleopatra, Anthony, Daniel C., Sibson, Nicola R.
Publicado 2016

(19)F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

por Leśniak, Robert K., Rydzik, Anna M., Kamps, Jos J. A. G., Kahn, Amjad, Claridge, Timothy D. W., Schofield, Christopher J.
Publicado 2019

Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans

por Hopkinson, Richard J., Leung, Ivanhoe K. H., Smart, Tristan J., Rose, Nathan R., Henry, Luc, Claridge, Timothy D. W., Schofield, Christopher J.
Publicado 2015

Terminalia bentzoë, a Mascarene Endemic Plant, Inhibits Human Hepatocellular Carcinoma Cells Growth In Vitro via G0/G1 Phase Cell Cycle Arrest

por Rummun, Nawraj, Rondeau, Philippe, Bourdon, Emmanuel, Pires, Elisabete, McCullagh, James, Claridge, Timothy D. W., Bahorun, Theeshan, Li, Wen-Wu, Neergheen, Vidushi S.
Publicado 2020