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An in silico hybrid continuum-/agent-based procedure to modelling cancer development: Interrogating the interplay amongst glioma invasion, vascularity and necrosis

This paper develops a three-dimensionalin silicohybrid model of cancer, which describes the multi-variate phenotypic behaviour of tumour and host cells. The model encompasses the role of cell migration and adhesion, the influence of the extracellular matrix, the effects of oxygen and nutrient availa...

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Detalles Bibliográficos
Autores principales: de Montigny, Jean, Iosif, Alexandros, Breitwieser, Lukas, Manca, Marco, Bauer, Roman, Vavourakis, Vasileios
Lenguaje:eng
Publicado: 2021
Materias:
Acceso en línea:https://dx.doi.org/10.1016/j.ymeth.2020.01.006
http://cds.cern.ch/record/2712065