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Challenges of Anti-Mesothelin CAR-T-Cell Therapy
SIMPLE SUMMARY: In recent years, chimeric antigen receptor (CAR)-T-cell therapy has achieved good results in hematological malignancies. Clinical trials on anti-MSLN CAR-T cells have shown that they have a high safety profile but limited efficacy. This article reviews the clinical research status, o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000068/ https://www.ncbi.nlm.nih.gov/pubmed/36900151 http://dx.doi.org/10.3390/cancers15051357 |