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Validation of p53 Immunohistochemistry (PAb240 Clone) in Canine Tumors with Next-Generation Sequencing (NGS) Analysis

SIMPLE SUMMARY: TP53 is a tumor-suppressor gene that is involved in cell cycle arrest, and its mutation is an event that is recognized to cause and contribute to carcinogenesis. Increased immunohistochemical expression of p53 in tumors has been associated with mutation of the gene; therefore, this c...

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Detalles Bibliográficos
Autores principales: Brunetti, Barbara, de Biase, Dario, Dellapina, Giulia, Muscatello, Luisa Vera, Ingravalle, Francesco, Tura, Giorgia, Bacci, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000222/
https://www.ncbi.nlm.nih.gov/pubmed/36899756
http://dx.doi.org/10.3390/ani13050899