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The Anti-Tumor Effect of the Newly Developed LAT1 Inhibitor JPH203 in Colorectal Carcinoma, According to a Comprehensive Analysis

SIMPLE SUMMARY: The large neutral amino acid transporter family (LAT1-4) plays an important role in the intracellular uptake of essential amino acids. Among them, LAT1 is specifically expressed in cancer cells. A novel LAT1-specific inhibitor, JPH203, is expected to cause cancer-specific starvation...

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Detalles Bibliográficos
Autores principales: Otani, Rina, Takigawa, Hidehiko, Yuge, Ryo, Shimizu, Daisuke, Ariyoshi, Misa, Miyamoto, Ryo, Kadota, Hiroki, Hiyama, Yuichi, Hayashi, Ryohei, Urabe, Yuji, Ishikawa, Akira, Oue, Naohide, Kitadai, Yasuhiko, Oka, Shiro, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000236/
https://www.ncbi.nlm.nih.gov/pubmed/36900176
http://dx.doi.org/10.3390/cancers15051383