Transcriptional Basis of Ca(2+) Remodeling Reversal Induced by Polyamine Synthesis Inhibition in Colorectal Cancer Cells

SIMPLE SUMMARY: The common activation of the c-Myc oncogene in colorectal cancer (CRC) induces the overexpression of ornithine decarboxylase (ODC), the limiting step in polyamine synthesis, which is a process blocked by α-Difluoromethylornithine (DFMO), an ODC suicide inhibitor and potential CRC tre...

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Detalles Bibliográficos
Autores principales: Pérez-Riesgo, Enrique, Hernando-Pérez, Elena, Feijóo, Verónica, Tajada, Sendoa, Núñez, Lucía, Villalobos, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000432/
https://www.ncbi.nlm.nih.gov/pubmed/36900391
http://dx.doi.org/10.3390/cancers15051600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000432/
https://www.ncbi.nlm.nih.gov/pubmed/36900391
http://dx.doi.org/10.3390/cancers15051600

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