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A Triphenylphosphonium-Functionalized Delivery System for an ATM Kinase Inhibitor That Ameliorates Doxorubicin Resistance in Breast Carcinoma Mammospheres

SIMPLE SUMMARY: Doxorubicin (DOX) is widely used in the treatment of breast cancer. However, resistance limits its effectiveness. In particular, breast cancer stem cells (BCSCs) are associated with DOX resistance. We have previously demonstrated the potential of a polymeric nanocarrier based on a su...

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Detalles Bibliográficos
Autores principales: Stagni, Venturina, Kaminari, Archontia, Contadini, Claudia, Barilà, Daniela, Sessa, Rosario Luigi, Sideratou, Zili, Vlahopoulos, Spiros A., Tsiourvas, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000448/
https://www.ncbi.nlm.nih.gov/pubmed/36900267
http://dx.doi.org/10.3390/cancers15051474