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Low Gut Microbial Diversity Augments Estrogen-Driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease

Although profibrotic cytokines, such as IL-17A and TGF-β1, have been implicated in the pathogenesis of interstitial lung disease (ILD), the interactions between gut dysbiosis, gonadotrophic hormones and molecular mediators of profibrotic cytokine expression, such as the phosphorylation of STAT3, hav...

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Detalles Bibliográficos
Autores principales: Chioma, Ozioma S., Mallott, Elizabeth, Shah-Gandhi, Binal, Wiggins, ZaDarreyal, Langford, Madison, Lancaster, Andrew William, Gelbard, Alexander, Wu, Hongmei, Johnson, Joyce E., Lancaster, Lisa, Wilfong, Erin M., Crofford, Leslie J., Montgomery, Courtney G., Van Kaer, Luc, Bordenstein, Seth, Newcomb, Dawn C., Drake, Wonder Puryear
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000459/
https://www.ncbi.nlm.nih.gov/pubmed/36899902
http://dx.doi.org/10.3390/cells12050766