Zinc Finger Protein 90 Knockdown Promotes Cisplatin Sensitivity via Nrf2/HO-1 Pathway in Ovarian Cancer Cell

SIMPLE SUMMARY: Our data suggested that cisplatin treatment generates reactive oxygen species (ROS) that modulate apoptotic proteins expression (p-P38, p-ERK, p-Akt, Bcl-2, Bax, active caspase-3). The anti-oxidative signal (Nrf2, HO-1, SOD) was also activated, which could inhibit cell migration (MMP...

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Detalles Bibliográficos
Autores principales: Wu, Ching-Hu, Feng, Chien-Wei, Wang, Chiu-Lin, Wen, Zhi-Hong, Long, Cheng-Yu, Tang, Feng-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000492/
https://www.ncbi.nlm.nih.gov/pubmed/36900383
http://dx.doi.org/10.3390/cancers15051586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000492/
https://www.ncbi.nlm.nih.gov/pubmed/36900383
http://dx.doi.org/10.3390/cancers15051586

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