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From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy

SIMPLE SUMMARY: Mild hyperthermia (mHT, 39–42 °C) is a potent modality when combined with existing radio-, chemo-, or immunotherapy, leading to enhanced microcirculatory blood flow and improved tumor oxygenation. Currently, the mechanisms responsible for these mHT-related effects are not fully under...

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Detalles Bibliográficos
Autores principales: Vaupel, Peter, Piazena, Helmut, Notter, Markus, Thomsen, Andreas R., Grosu, Anca-L., Scholkmann, Felix, Pockley, Alan Graham, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000497/
https://www.ncbi.nlm.nih.gov/pubmed/36900190
http://dx.doi.org/10.3390/cancers15051394