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Blocking Store-Operated Ca(2+) Entry to Protect HL-1 Cardiomyocytes from Epirubicin-Induced Cardiotoxicity
Epirubicin (EPI) is one of the most widely used anthracycline chemotherapy drugs, yet its cardiotoxicity severely limits its clinical application. Altered intracellular Ca(2+) homeostasis has been shown to contribute to EPI-induced cell death and hypertrophy in the heart. While store-operated Ca(2+)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000558/ https://www.ncbi.nlm.nih.gov/pubmed/36899859 http://dx.doi.org/10.3390/cells12050723 |