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Blocking Store-Operated Ca(2+) Entry to Protect HL-1 Cardiomyocytes from Epirubicin-Induced Cardiotoxicity

Epirubicin (EPI) is one of the most widely used anthracycline chemotherapy drugs, yet its cardiotoxicity severely limits its clinical application. Altered intracellular Ca(2+) homeostasis has been shown to contribute to EPI-induced cell death and hypertrophy in the heart. While store-operated Ca(2+)...

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Detalles Bibliográficos
Autores principales: Liu, Xian, Chang, Yan, Choi, Sangyong, Cai, Chuanxi, Zhang, Xiaoli, Pan, Zui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000558/
https://www.ncbi.nlm.nih.gov/pubmed/36899859
http://dx.doi.org/10.3390/cells12050723