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A Biterm Topic Model for Sparse Mutation Data

SIMPLE SUMMARY: We developed an efficient method for analyzing sparse mutation data based on mutation co-occurrence to infer the underlying numbers of mutational signatures and sample clusters that gave rise to the data. ABSTRACT: Mutational signature analysis promises to reveal the processes that s...

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Detalles Bibliográficos
Autores principales: Sason, Itay, Chen, Yuexi, Leiserson, Mark D. M., Sharan, Roded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000560/
https://www.ncbi.nlm.nih.gov/pubmed/36900390
http://dx.doi.org/10.3390/cancers15051601