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A Biterm Topic Model for Sparse Mutation Data
SIMPLE SUMMARY: We developed an efficient method for analyzing sparse mutation data based on mutation co-occurrence to infer the underlying numbers of mutational signatures and sample clusters that gave rise to the data. ABSTRACT: Mutational signature analysis promises to reveal the processes that s...
Autores principales: | Sason, Itay, Chen, Yuexi, Leiserson, Mark D. M., Sharan, Roded |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000560/ https://www.ncbi.nlm.nih.gov/pubmed/36900390 http://dx.doi.org/10.3390/cancers15051601 |
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