Cargando…
Heparan Sulfates Regulate Axonal Excitability and Context Generalization through Ca(2+)/Calmodulin-Dependent Protein Kinase II
Our previous studies demonstrated that enzymatic removal of highly sulfated heparan sulfates with heparinase 1 impaired axonal excitability and reduced expression of ankyrin G at the axon initial segments in the CA1 region of the hippocampus ex vivo, impaired context discrimination in vivo, and incr...
Autores principales: | Song, Inseon, Kuznetsova, Tatiana, Baidoe-Ansah, David, Mirzapourdelavar, Hadi, Senkov, Oleg, Hayani, Hussam, Mironov, Andrey, Kaushik, Rahul, Druzin, Michael, Johansson, Staffan, Dityatev, Alexander |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000602/ https://www.ncbi.nlm.nih.gov/pubmed/36899880 http://dx.doi.org/10.3390/cells12050744 |
Ejemplares similares
-
Heparan Sulfates Support Pyramidal Cell Excitability, Synaptic Plasticity, and Context Discrimination
por: Minge, Daniel, et al.
Publicado: (2017) -
Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix
por: Hayani, Hussam, et al.
Publicado: (2018) -
Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3
por: Baidoe-Ansah, David, et al.
Publicado: (2022) -
Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice
por: Strackeljan, Luisa, et al.
Publicado: (2021) -
A novel versatile hybrid infusion-multielectrode recording (HIME) system for acute drug delivery and multisite acquisition of neuronal activity in freely moving mice
por: Senkov, Oleg, et al.
Publicado: (2015)