Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK

The master kinase LKB1 is a key regulator of se veral cellular processes, including cell proliferation, cell polarity and cellular metabolism. It phosphorylates and activates several downstream kinases, including AMP-dependent kinase, AMPK. Activation of AMPK by low energy supply and phosphorylation...

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Detalles Bibliográficos
Autores principales: Borkowsky, Sarah, Gass, Maximilian, Alavizargar, Azadeh, Hanewinkel, Johannes, Hallstein, Ina, Nedvetsky, Pavel, Heuer, Andreas, Krahn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000615/
https://www.ncbi.nlm.nih.gov/pubmed/36899949
http://dx.doi.org/10.3390/cells12050812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000615/
https://www.ncbi.nlm.nih.gov/pubmed/36899949
http://dx.doi.org/10.3390/cells12050812

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