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Blocking EREG/GPX4 Sensitizes Head and Neck Cancer to Cetuximab through Ferroptosis Induction

(1) Background: Epiregulin (EREG) is a ligand of EGFR and ErB4 involved in the development and the progression of various cancers including head and neck squamous cell carcinoma (HNSCC). Its overexpression in HNSCC is correlated with short overall survival and progression-free survival but predictiv...

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Detalles Bibliográficos
Autores principales: Jehl, Aude, Conrad, Ombline, Burgy, Mickaël, Foppolo, Sophie, Vauchelles, Romain, Ronzani, Carole, Etienne-Selloum, Nelly, Chenard, Marie-Pierre, Danic, Aurélien, Dourlhes, Thomas, Thibault, Claire, Schultz, Philippe, Dontenwill, Monique, Martin, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000618/
https://www.ncbi.nlm.nih.gov/pubmed/36899869
http://dx.doi.org/10.3390/cells12050733