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17⍺-Estradiol Protects against HIV-1 Tat-Induced Endolysosome Dysfunction and Dendritic Impairments in Neurons

HIV-1 Tat continues to play an important role in the development of HIV-associated neurocognitive disorders (HAND), which persist in 15–55% of people living with HIV even with virological control. In the brain, Tat is present on neurons, where Tat exerts direct neuronal damaging effects by, at least...

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Detalles Bibliográficos
Autores principales: Datta, Gaurav, Miller, Nicole M., Chen, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000619/
https://www.ncbi.nlm.nih.gov/pubmed/36899948
http://dx.doi.org/10.3390/cells12050813