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Intrahippocampal Inoculation of Aβ(1–42) Peptide in Rat as a Model of Alzheimer’s Disease Identified MicroRNA-146a-5p as Blood Marker with Anti-Inflammatory Function in Astrocyte Cells

Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers of Alzheimer’s disease (AD). Here, we investigated the panel of expressed blood miRNAs in response to aggregated Aβ(1–42) peptides infused in the hippocampus of adult rats to mimic events of the ear...

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Detalles Bibliográficos
Autores principales: Aquino, Ruth, de Concini, Vidian, Dhenain, Marc, Lam, Suzanne, Gosset, David, Baquedano, Laura, Forero, Manuel G., Menuet, Arnaud, Baril, Patrick, Pichon, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000752/
https://www.ncbi.nlm.nih.gov/pubmed/36899831
http://dx.doi.org/10.3390/cells12050694