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DNA Repair Deficiency Regulates Immunity Response in Cancers: Molecular Mechanism and Approaches for Combining Immunotherapy

SIMPLE SUMMARY: DNA repair pathways play a crucial role in maintaining the stability of a cell’s genetic material. When these pathways are defective, it can lead to genomic instability in cancer cells, which can increase their ability to stimulate an immune response. Inhibiting DNA damage response,...

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Detalles Bibliográficos
Autores principales: Xu, Yi, Nowsheen, Somaira, Deng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000854/
https://www.ncbi.nlm.nih.gov/pubmed/36900418
http://dx.doi.org/10.3390/cancers15051619