ITPA Polymorphisms and the Incidence of Toxicities in Children with Acute Lymphoblastic Leukemia

BACKGROUND: 6-Mercaptopurine (6-MP), a thiopurine agent, is a essential medication for treating pediatric acute lymphoblastic leukemia (ALL). However, its side effects of neutropenia and hepatotoxicity might interrupt treatment, resulting in poor outcomes. Inosine triphosphate pyrophosphatase (ITPA)...

Descripción completa

Detalles Bibliográficos
Autores principales: Svasdisant, Patpetra, Glomglao, Waraporn, Siraprapapat, Preeyanun, Inthararujikul, Wiyakan, Tachavanich, Kalaya, Boonthimat, Chetsada, Ardsiri, Sakkarin, Chansing, Kochpinchon, Sriprach, Suwimon, Tongsai, Sasima, Sinlapamongkolkul, Phakatip, Sanpakit, Kleebsabai, Buaboonnam, Jassada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000882/
https://www.ncbi.nlm.nih.gov/pubmed/36908869
http://dx.doi.org/10.4084/MJHID.2023.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000882/
https://www.ncbi.nlm.nih.gov/pubmed/36908869
http://dx.doi.org/10.4084/MJHID.2023.024

Ejemplares similares