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ITPA Polymorphisms and the Incidence of Toxicities in Children with Acute Lymphoblastic Leukemia

BACKGROUND: 6-Mercaptopurine (6-MP), a thiopurine agent, is a essential medication for treating pediatric acute lymphoblastic leukemia (ALL). However, its side effects of neutropenia and hepatotoxicity might interrupt treatment, resulting in poor outcomes. Inosine triphosphate pyrophosphatase (ITPA)...

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Detalles Bibliográficos
Autores principales:	Svasdisant, Patpetra, Glomglao, Waraporn, Siraprapapat, Preeyanun, Inthararujikul, Wiyakan, Tachavanich, Kalaya, Boonthimat, Chetsada, Ardsiri, Sakkarin, Chansing, Kochpinchon, Sriprach, Suwimon, Tongsai, Sasima, Sinlapamongkolkul, Phakatip, Sanpakit, Kleebsabai, Buaboonnam, Jassada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Università Cattolica del Sacro Cuore 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000882/ https://www.ncbi.nlm.nih.gov/pubmed/36908869 http://dx.doi.org/10.4084/MJHID.2023.024

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