Comparative and Temporal Characterization of LPS and Blue-Light-Induced TLR4 Signal Transduction and Gene Expression in Optogenetically Manipulated Endothelial Cells

In endothelial cells (ECs), stimulation of Toll-like receptor 4 (TLR4) by the endotoxin lipopolysaccharide (LPS) induces the release of diverse pro-inflammatory mediators, beneficial in controlling bacterial infections. However, their systemic secretion is a main driver of sepsis and chronic inflamm...

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Detalles Bibliográficos
Autores principales: Stierschneider, Anna, Neuditschko, Benjamin, Colleselli, Katrin, Hundsberger, Harald, Herzog, Franz, Wiesner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000987/
https://www.ncbi.nlm.nih.gov/pubmed/36899833
http://dx.doi.org/10.3390/cells12050697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000987/
https://www.ncbi.nlm.nih.gov/pubmed/36899833
http://dx.doi.org/10.3390/cells12050697

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