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Comparative and Temporal Characterization of LPS and Blue-Light-Induced TLR4 Signal Transduction and Gene Expression in Optogenetically Manipulated Endothelial Cells
In endothelial cells (ECs), stimulation of Toll-like receptor 4 (TLR4) by the endotoxin lipopolysaccharide (LPS) induces the release of diverse pro-inflammatory mediators, beneficial in controlling bacterial infections. However, their systemic secretion is a main driver of sepsis and chronic inflamm...
Autores principales: | Stierschneider, Anna, Neuditschko, Benjamin, Colleselli, Katrin, Hundsberger, Harald, Herzog, Franz, Wiesner, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000987/ https://www.ncbi.nlm.nih.gov/pubmed/36899833 http://dx.doi.org/10.3390/cells12050697 |
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