Predictive and Prognostic Value of Oncogene Mutations and Microsatellite Instability in Locally-Advanced Rectal Cancer Treated with Neoadjuvant Radiation-Based Therapy: A Systematic Review and Meta-Analysis

SIMPLE SUMMARY: Identification of novel molecular markers of pathological complete response (pCR) to preoperative radiation-based therapy in locally advanced rectal cancer (LARC) is strongly needed. Given the established predictive and/or prognostic role of somatic mutations in key oncogenes (RAS, T...

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Detalles Bibliográficos
Autores principales: De Mattia, Elena, Polesel, Jerry, Mezzalira, Silvia, Palazzari, Elisa, Pollesel, Sara, Toffoli, Giuseppe, Cecchin, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Systematic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001009/
https://www.ncbi.nlm.nih.gov/pubmed/36900260
http://dx.doi.org/10.3390/cancers15051469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001009/
https://www.ncbi.nlm.nih.gov/pubmed/36900260
http://dx.doi.org/10.3390/cancers15051469

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