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Estrogen Mediates the Sexual Dimorphism of GT1b-Induced Central Pain Sensitization

We have previously reported that the intrathecal (i.t.) administration of GT1b, a ganglioside, induces spinal cord microglia activation and central pain sensitization as an endogenous agonist of Toll-like receptor 2 on microglia. In this study, we investigated the sexual dimorphism of GT1b-induced c...

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Detalles Bibliográficos
Autores principales: Lee, Jaesung, Chung, Seohyun, Hwang, Minkyu, Kwon, Yeongkag, Han, Seung Hyun, Lee, Sung Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001026/
https://www.ncbi.nlm.nih.gov/pubmed/36899944
http://dx.doi.org/10.3390/cells12050808