Host Cell Restriction Factors Blocking Efficient Vector Transduction: Challenges in Lentiviral and Adeno-Associated Vector Based Gene Therapies

Gene therapy relies on the delivery of genetic material to the patient’s cells in order to provide a therapeutic treatment. Two of the currently most used and efficient delivery systems are the lentiviral (LV) and adeno-associated virus (AAV) vectors. Gene therapy vectors must successfully attach, e...

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Detalles Bibliográficos
Autor principal: Coroadinha, Ana Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001033/
https://www.ncbi.nlm.nih.gov/pubmed/36899868
http://dx.doi.org/10.3390/cells12050732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001033/
https://www.ncbi.nlm.nih.gov/pubmed/36899868
http://dx.doi.org/10.3390/cells12050732

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