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Routine EWS Fusion Analysis in the Oncology Clinic to Identify Cancer-Specific Peptide Sequence Patterns That Span Breakpoints in Ewing Sarcoma and DSRCT
SIMPLE SUMMARY: EWS-based fusions are aberrantly fused genes that drive Ewing sarcoma and desmoplastic small round cell tumor (DSRCT). Fusion data may be useful for personalized mRNA vaccines but are not yet routinely obtained in clinical practice. We present our workflow for the characterization of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001040/ https://www.ncbi.nlm.nih.gov/pubmed/36900411 http://dx.doi.org/10.3390/cancers15051623 |