Routine EWS Fusion Analysis in the Oncology Clinic to Identify Cancer-Specific Peptide Sequence Patterns That Span Breakpoints in Ewing Sarcoma and DSRCT

SIMPLE SUMMARY: EWS-based fusions are aberrantly fused genes that drive Ewing sarcoma and desmoplastic small round cell tumor (DSRCT). Fusion data may be useful for personalized mRNA vaccines but are not yet routinely obtained in clinical practice. We present our workflow for the characterization of...

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Detalles Bibliográficos
Autores principales: Anderson, Peter M., Tu, Zheng Jin, Kilpatrick, Scott E., Trucco, Matteo, Hanna, Rabi, Chan, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001040/
https://www.ncbi.nlm.nih.gov/pubmed/36900411
http://dx.doi.org/10.3390/cancers15051623

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