5-Fluorouracil Suppresses Colon Tumor through Activating the p53-Fas Pathway to Sensitize Myeloid-Derived Suppressor Cells to FasL(+) Cytotoxic T Lymphocyte Cytotoxicity

SIMPLE SUMMARY: 5-Fluorouracil (5-FU), in combination with various therapeutic agents, is the main strategy for patients with high risk of stage 2, and advanced stages of, human colorectal cancer. Although 5-FU-based chemotherapy causes myeloid cell suppression, which has long been considered as a m...

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Detalles Bibliográficos
Autores principales: Yang, Yingcui, Zhang, Mingqing, Zhang, Yongdan, Liu, Kebin, Lu, Chunwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001142/
https://www.ncbi.nlm.nih.gov/pubmed/36900354
http://dx.doi.org/10.3390/cancers15051563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001142/
https://www.ncbi.nlm.nih.gov/pubmed/36900354
http://dx.doi.org/10.3390/cancers15051563

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