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Molecularly Targeted Therapy in Acute Myeloid Leukemia: Current Treatment Landscape and Mechanisms of Response and Resistance

SIMPLE SUMMARY: Molecularly targeted therapy is now a standard treatment option for patients with acute myeloid leukemia and IDH1/2 or FLT3 mutations. This review summarizes the current treatment landscape of IDH and FLT3 inhibitors and emerging targeted therapies for the treatment of AML. ABSTRACT:...

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Detalles Bibliográficos
Autores principales: Lachowiez, Curtis A., DiNardo, Courtney D., Loghavi, Sanam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001191/
https://www.ncbi.nlm.nih.gov/pubmed/36900407
http://dx.doi.org/10.3390/cancers15051617