Perfusion Air Culture of Precision-Cut Tumor Slices: An Ex Vivo System to Evaluate Individual Drug Response under Controlled Culture Conditions

Precision-cut tumor slices (PCTS) maintain tissue heterogeneity concerning different cell types and preserve the tumor microenvironment (TME). Typically, PCTS are cultured statically on a filter support at an air–liquid interface, which gives rise to intra-slice gradients during culture. To overcome...

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Detalles Bibliográficos
Autores principales: Dong, Meng, Böpple, Kathrin, Thiel, Julia, Winkler, Bernd, Liang, Chunguang, Schueler, Julia, Davies, Emma J., Barry, Simon T., Metsalu, Tauno, Mürdter, Thomas E., Sauer, Georg, Ott, German, Schwab, Matthias, Aulitzky, Walter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001200/
https://www.ncbi.nlm.nih.gov/pubmed/36899943
http://dx.doi.org/10.3390/cells12050807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001200/
https://www.ncbi.nlm.nih.gov/pubmed/36899943
http://dx.doi.org/10.3390/cells12050807

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