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Preclinical PET Imaging of Tumor Cell Death following Therapy Using Gallium-68-Labeled C2Am

SIMPLE SUMMARY: There is an unmet clinical need for imaging agents capable of detecting the presence, extent, and distribution of tumor cell death following treatment. We describe here a gallium-68-labeled derivative of the C2A domain of Synaptotagmin-I ((68)Ga-C2Am), which binds to the phosphatidyl...

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Detalles Bibliográficos
Autores principales: Bulat, Flaviu, Hesse, Friederike, Attili, Bala, Solanki, Chandra, Mendichovszky, Iosif A., Aigbirhio, Franklin, Leeper, Finian J., Brindle, Kevin M., Neves, André A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001225/
https://www.ncbi.nlm.nih.gov/pubmed/36900353
http://dx.doi.org/10.3390/cancers15051564