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Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function

Advanced glycation end products (AGEs) contribute significantly to vascular dysfunction (VD) in diabetes. Decreased nitric oxide (NO) is a hallmark in VD. In endothelial cells, NO is produced by endothelial NO synthase (eNOS) from L-arginine. Arginase competes with NOS for L-arginine to produce urea...

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Detalles Bibliográficos
Autores principales: Alzayadneh, Ebaa M., Shatanawi, Alia, Caldwell, R. William, Caldwell, Ruth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001288/
https://www.ncbi.nlm.nih.gov/pubmed/36899931
http://dx.doi.org/10.3390/cells12050795