Diagnostic Predictors of Immunotherapy Response in Head and Neck Squamous Cell Carcinoma

Programmed cell death ligand-1 (PD-L1) binds PD-1 on CD(8+) lymphocytes, inhibiting their cytotoxic action. Its aberrant expression by head and neck squamous cell carcinoma (HNSCC) cells leads to immune escape. Pembrolizumab and nivolumab, two humanized monoclonal antibodies against PD-1, have been...

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Detalles Bibliográficos
Autores principales: Meliante, Piero Giuseppe, Zoccali, Federica, de Vincentiis, Marco, Ralli, Massimo, Petrella, Carla, Fiore, Marco, Minni, Antonio, Barbato, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001329/
https://www.ncbi.nlm.nih.gov/pubmed/36900006
http://dx.doi.org/10.3390/diagnostics13050862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001329/
https://www.ncbi.nlm.nih.gov/pubmed/36900006
http://dx.doi.org/10.3390/diagnostics13050862

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