Polymorphism and Ligand Binding Modulate Fast Dynamics of Human Telomeric G-Quadruplexes

Telomeric G-quadruplexes (G4s) are promising targets in the design and development of anticancer drugs. Their actual topology depends on several factors, resulting in structural polymorphism. In this study, we investigate how the fast dynamics of the telomeric sequence AG [Formula: see text] (TTAG [...

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Detalles Bibliográficos
Autores principales: Bertini, Luca, Libera, Valeria, Ripanti, Francesca, Natali, Francesca, Paolantoni, Marco, Orecchini, Andrea, Nucara, Alessandro, Petrillo, Caterina, Comez, Lucia, Paciaroni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001961/
https://www.ncbi.nlm.nih.gov/pubmed/36901712
http://dx.doi.org/10.3390/ijms24054280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001961/
https://www.ncbi.nlm.nih.gov/pubmed/36901712
http://dx.doi.org/10.3390/ijms24054280

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