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A Nanoenzyme Constructed from Manganese and Strandberg-Type Phosphomolybdate with Versatility in Antioxidant and Modulating Conformation of Aβ Protein Misfolding Aggregates In Vitro

Amyloid β-peptide (Aβ) misfolding aggregates with β-sheet structures and surplus reactive oxygen species (ROS) are both considered to be the culprit of neuronal toxicity in Alzheimer’s disease (AD). Therefore, modulating the misfolding mode of Aβ and inhibiting ROS simultaneous has become an importa...

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Detalles Bibliográficos
Autores principales: Hua, Jiai, Wang, Feng, Wei, Xueman, Qin, Yuxin, Lian, Jiameng, Wu, Jianhong, Ma, Pengtao, Ma, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002135/
https://www.ncbi.nlm.nih.gov/pubmed/36901748
http://dx.doi.org/10.3390/ijms24054317