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PPP3R1 Promotes MSCs Senescence by Inducing Plasma Membrane Depolarization and Increasing Ca(2+) Influx

Aging of mesenchymal stem cells(MSCs) has been widely reported to be strongly associated with aging-related diseases, including osteoporosis (OP). In particular, the beneficial functions of mesenchymal stem cells decline with age, limiting their therapeutic efficacy in age-related bone loss diseases...

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Detalles Bibliográficos
Autores principales: Li, Molin, Gong, Weimin, Chen, Jie, Zhang, Yining, Ma, Yufei, Tu, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002166/
https://www.ncbi.nlm.nih.gov/pubmed/36901851
http://dx.doi.org/10.3390/ijms24054421