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Design and Validation of a Custom Next-Generation Sequencing Panel in Pediatric Acute Lymphoblastic Leukemia

The molecular landscape of acute lymphoblastic leukemia (ALL) is highly heterogeneous, and genetic lesions are clinically relevant for diagnosis, risk stratification, and treatment guidance. Next-generation sequencing (NGS) has become an essential tool for clinical laboratories, where disease-target...

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Detalles Bibliográficos
Autores principales: Gil, José Vicente, Such, Esperanza, Sargas, Claudia, Simarro, Javier, Miralles, Alberto, Pérez, Gema, de Juan, Inmaculada, Palanca, Sarai, Avetisyan, Gayane, Santiago, Marta, Fuentes, Carolina, Fernández, José María, Vicente, Ana Isabel, Romero, Samuel, Llop, Marta, Barragán, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002321/
https://www.ncbi.nlm.nih.gov/pubmed/36901871
http://dx.doi.org/10.3390/ijms24054440