COL7A1 Editing via RNA Trans-Splicing in RDEB-Derived Skin Equivalents

Mutations in the COL7A1 gene lead to malfunction, reduction or complete absence of type VII collagen (C7) in the skin’s basement membrane zone (BMZ), impairing skin integrity. In epidermolysis bullosa (EB), more than 800 mutations in COL7A1 have been reported, leading to the dystrophic form of EB (D...

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Detalles Bibliográficos
Autores principales: Liemberger, Bernadette, Bischof, Johannes, Ablinger, Michael, Hainzl, Stefan, Murauer, Eva M., Lackner, Nina, Ebner, Patricia, Kocher, Thomas, Nyström, Alexander, Wally, Verena, Mayr, Elisabeth, Guttmann-Gruber, Christina, Hofbauer, Josefina Piñón, Bauer, Johann W., Koller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002491/
https://www.ncbi.nlm.nih.gov/pubmed/36901775
http://dx.doi.org/10.3390/ijms24054341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002491/
https://www.ncbi.nlm.nih.gov/pubmed/36901775
http://dx.doi.org/10.3390/ijms24054341

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