Direct Oral FXa Inhibitors Binding to Human Serum Albumin: Spectroscopic, Calorimetric, and Computational Studies

Direct FXa inhibitors are an important class of bioactive molecules (rivaroxaban, apixaban, edoxaban, and betrixaban) applied for thromboprophylaxis in diverse cardiovascular pathologies. The interaction of active compounds with human serum albumin (HSA), the most abundant protein in blood plasma, i...

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Detalles Bibliográficos
Autores principales: Mariño-Ocampo, Nory, Rodríguez, Diego F., Guerra Díaz, Daniel, Zúñiga-Núñez, Daniel, Duarte, Yorley, Fuentealba, Denis, Zacconi, Flavia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002493/
https://www.ncbi.nlm.nih.gov/pubmed/36902328
http://dx.doi.org/10.3390/ijms24054900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002493/
https://www.ncbi.nlm.nih.gov/pubmed/36902328
http://dx.doi.org/10.3390/ijms24054900

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