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Resolvin E1 improves efferocytosis and rescues severe aplastic anemia in mice

Current treatments for severe aplastic anemia (SAA) rely on hematopoietic stem cell (HSC) transplantation and immunosuppressive therapies, however these treatments are not always effective. While immune-mediated destruction and inflammation are known drivers of SAA, the underlying mechanisms that le...

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Detalles Bibliográficos
Autores principales: Grazda, Rachel, Seyfried, Allison N., Maddipatti, Krishna Rao, Fredman, Gabrielle, MacNamara, Katherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002513/
https://www.ncbi.nlm.nih.gov/pubmed/36909559
http://dx.doi.org/10.1101/2023.02.15.528688