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Co-Transplantation of Barcoded Lymphoid-Primed Multipotent (LMPP) and Common Lymphocyte (CLP) Progenitors Reveals a Major Contribution of LMPP to the Lymphoid Lineage

T cells have the potential to maintain immunological memory and self-tolerance by recognizing antigens from pathogens or tumors. In pathological situations, failure to generate de novo T cells causes immunodeficiency resulting in acute infections and complications. Hematopoietic stem cells (HSC) tra...

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Detalles Bibliográficos
Autores principales: Michaels, Victoria, Chalabi, Smahane, Legrand, Agnes, Renard, Julie, Tejerina, Emmanuel, Daouya, Marina, Fabrega, Sylvie, Megret, Jérôme, Olaso, Robert, Boland, Anne, Deleuze, Jean-François, Battail, Christophe, Tronik-Le Roux, Diana, Ezine, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002536/
https://www.ncbi.nlm.nih.gov/pubmed/36901798
http://dx.doi.org/10.3390/ijms24054368