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Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate

Alzheimer’s disease (AD) is characterized by synaptic failure and neuronal loss. Recently, we demonstrated that artemisinins restored the levels of key proteins of inhibitory GABAergic synapses in the hippocampus of APP/PS1 mice, a model of cerebral amyloidosis. In the present study, we analyzed the...

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Detalles Bibliográficos
Autores principales: Kuhse, Jochen, Groeneweg, Femke, Kins, Stefan, Gorgas, Karin, Nawrotzki, Ralph, Kirsch, Joachim, Kiss, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002537/
https://www.ncbi.nlm.nih.gov/pubmed/36902054
http://dx.doi.org/10.3390/ijms24054623