A Novel Ambroxol-Derived Tetrahydroquinazoline with a Potency against SARS-CoV-2 Proteins

We report synthesis of a novel 1,2,3,4-tetrahydroquinazoline derivative, named 2-(6,8-dibromo-3-(4-hydroxycyclohexyl)-1,2,3,4-tetrahydroquinazolin-2-yl)phenol (1), which was obtained from the hydrochloride of 4-((2-amino-3,5-dibromobenzyl)amino)cyclohexan-1-ol (ambroxol hydrochloride) and salicylald...

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Detalles Bibliográficos
Autores principales: Krysantieva, Alena I., Voronina, Julia K., Safin, Damir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002583/
https://www.ncbi.nlm.nih.gov/pubmed/36902093
http://dx.doi.org/10.3390/ijms24054660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002583/
https://www.ncbi.nlm.nih.gov/pubmed/36902093
http://dx.doi.org/10.3390/ijms24054660

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