The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen Chlamydia trachomatis secretes Cdu1 (ChlaDUB1), a dual deub...

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Detalles Bibliográficos
Autores principales: Bastidas, Robert J., Kędzior, Mateusz, Davidson, Robert K., Walsh, Stephen C., Dolat, Lee, Sixt, Barbara S., Pruneda, Jonathan N., Coers, Jörn, Valdivia, Raphael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002621/
https://www.ncbi.nlm.nih.gov/pubmed/36909574
http://dx.doi.org/10.1101/2023.02.28.530337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002621/
https://www.ncbi.nlm.nih.gov/pubmed/36909574
http://dx.doi.org/10.1101/2023.02.28.530337

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