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The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen Chlamydia trachomatis secretes Cdu1 (ChlaDUB1), a dual deub...
Autores principales: | Bastidas, Robert J., Kędzior, Mateusz, Davidson, Robert K., Walsh, Stephen C., Dolat, Lee, Sixt, Barbara S., Pruneda, Jonathan N., Coers, Jörn, Valdivia, Raphael H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002621/ https://www.ncbi.nlm.nih.gov/pubmed/36909574 http://dx.doi.org/10.1101/2023.02.28.530337 |
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