Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

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Pptc7 is a resident mitochondrial phosphatase essential for maintaining proper mitochondrial content and function. Newborn mice lacking Pptc7 exhibit aberrant mitochondrial protein phosphorylation, suffer from a range of metabolic defects, and fail to survive beyond one day after birth. Using an ind...

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Detalles Bibliográficos
Autores principales: Niemi, Natalie M., Serrano, Lia R., Muehlbauer, Laura K., Balnis, Catie, Kozul, Keri-Lyn, Rashan, Edrees H., Shishkova, Evgenia, Schueler, Kathryn L., Keller, Mark P., Attie, Alan D., Pagan, Julia, Coon, Joshua J., Pagliarini, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002655/
https://www.ncbi.nlm.nih.gov/pubmed/36909604
http://dx.doi.org/10.1101/2023.02.28.530351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002655/
https://www.ncbi.nlm.nih.gov/pubmed/36909604
http://dx.doi.org/10.1101/2023.02.28.530351

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